Our dog Gunner, a boxer, had a cough for over 18months, and 3 vets later, 2 courses of antibiotics for "bronchitis", and every test available he got significantly worse. Lost 20 lbs and lost appetitie, lethargic, constant cough. Xray showed snowstorm in lungs. More tests - vets kept thinking it was a cancer that matasticized to the lungs that they just couldn't find. We did research and became convinced it was blasto or histo - and we are in Florida! Vets are very unfamiliar with this. We demanded itraconazole prescription figuring "what could it hurt" as we were losing him. In the first week of 3-100mg/day dose he stopped coughing for a while and actually perked up though the appetite faded quickly (as we expected). Now 14 days into itra therapy (we scaled back the dose after 7 days to balance the anorexia) and we have a refill on the script coming from Canada for a 90 day initial treatment.
However, Gunner now refuses to eat anything. We have tried virtually everything on the list and are cooking him 4 different meals at times every 4 hours. Chicken, broth, pork, ground beef, stuffing, mashed potatoes, cheese, hot dogs, bologna - you name it and we have tried it. We are now down to force feeding ensure plus through a turkey baster every 4-6 hours with the pills. Some good signs initially was a discharge of the dead yeasty stuff coming out when he coughed. But now he sounds full of fluid and pants shallowly. He is coughing continuously and clear liquid and even "foamy bubbles of spit" come out. He seems worse now 14 days in than he did at 7. He wants nothing to do with food and doesn't even like to get up. Some lameness in the front right leg when he first gets up that he "walks off."
I know there is no "normal" progress in these cases, but he is so thin and we are so sad and scared. We've even tried the bronchial dialators (no effect). Can the lungs fill up with fluid as the fungus dies and "drown" him? Are we doing everything we can? Please, are there any words of encouragement, because now we worry that we are verging on inhumane and question whether to continue. Are we helping or prolonging his pain?
Scott